CCL17 is one of the few chemokines that are not stored in the body, except in the thymus; these chemokines are made when needed by dendritic cells, macrophages, and monocytes. CCL17 is expressed constitutively in the thymus, but only transiently in phytohemagglutinin-stimulated … Meer weergeven CCL17 is a powerful chemokine produced in the thymus and by antigen-presenting cells like dendritic cells, macrophages, and monocytes. CCL17 plays a complex role in cancer. It attracts T-regulatory cells allowing for … Meer weergeven CCL17 (CC chemokine ligand 17) was initially named TARC (thymus- and activation-regulated chemokine) when first isolated in 1996. It was later renamed CCL17 as … Meer weergeven This chemokine is very important in the human body’s response to cancers. While it sometimes allows cancer to invade more rapidly, it more often helps the human body fight … Meer weergeven CCL17 is known to help leukocytes (and especially eosinophils) target their response to skin-located pathogens. This often occurs … Meer weergeven Cytokines, like CCL17, help cells communicate with one another, and stimulate cell movement. Chemokines are a type of cytokine that attract white blood cells to sites … Meer weergeven Like many cytokines, CCL17 is inflammatory, so while it plays a largely helpful role in attacking cancers, it can induce inflammatory diseases, including allergic skin … Meer weergeven In humans the gene for CCL17 is located on chromosome 16 along with other chemokines including CCL22 and CX3CL1. Meer weergeven WebCCL17 is constitutively expressed in the thymus and, under activation, in several cell types. CCL17-mediated recruitment of Th2 cells and CLA + CD4 + T cells plays a key role in allergic diseases like atopic dermatitis, allergic asthma, allergic rhinitis, and …
MIP-4 Polyclonal Antibody (500-P108-1MG)
Web14 aug. 2024 · We recently found that the chemokine, CCL17, is the most highly up-regulated gene in GM-CSF-treated human monocytes and, unlike TNF and IL-1β, is secreted at high levels by GM-CSF-treated monocytes and mouse macrophages ( 26 ). WebHuman CCL17, also known as thymus and activation regulated chemokine (TARC), was initially isolated from phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 is constitutively expressed in the thymus and under activation in several cell types. baraonda pokemon
Human CCL17/TARC Antibody AF364: R&D Systems
WebThe Thermo Scientific™ Human CCL17 (TARC) ELISA Kit is an enzyme-linked immunosorbent assay for measuring Human CCL17 in serum, plasma, and cell culture media. Rev 1.00 Effective Date: 10 FEB 2015 For Research Use Only. Not for use in diagnostic procedures. WebThe Quantikine™ Human CCL17/TARC Immunoassay kit is a 3.5 hour solid phase ELISA designed to measure human TARC in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human TARC and antibodies raised against the recombinant factor. It has been shown to accurately quantitate recombinant human … WebTarget Information. TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. baraonda orari